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Peste des Petits Ruminants in Sheep and Goats
#1
What is PPR? (Peste des Petits Ruminants)

PPR is a highly contagious viral disease that affects small ruminants like sheep and goats. It spreads quickly and can kill a large number of animals, causing huge losses for farmers. The virus mainly attacks the respiratory system (lungs, nose, throat) and the digestive system (stomach and intestines).

Common Symptoms

Fever

Loss of appetite

Diarrhea (sometimes bloody)

Nasal and eye discharge

Coughing and difficulty breathing

Mouth sores and drooling

Weakness and lethargy

High mortality in young or unvaccinated animals


PPR is a major problem in Africa, Asia, and the Middle East, threatening farmers’ income and food security.

Types of PPR Vaccines

1. Live-attenuated vaccines

The main type used to prevent PPR

Usually gives long-lasting protection with just one dose



2. DIVA vaccines

Newer vaccines under development

Help tell the difference between animals infected naturally and those vaccinated

Useful for monitoring and eradication programs



3. Recombinant vaccines

Made using specific viral proteins to trigger immunity

Still being researched




How PPR Vaccines Protect Animals

Immune response: Vaccines train the animal’s body to fight the virus using both antibodies and immune cells

Protective antibodies: These prevent the real PPR virus from causing disease


How Vaccines are Given

Usually given under the skin (subcutaneous injection)

Researchers are exploring easier methods, like mixing the vaccine in feed for large herds

Vaccines are safe and effective, protecting animals for several years


Challenges and What’s Next

Cold chain: Vaccines must be kept cool during transport and storage, especially in hot climates, or they may lose effectiveness

Vaccine failure: Sometimes vaccines don’t work if they go bad due to poor handling

Eradication goal: Organizations like the FAO and WOAH aim to completely eliminate PPR globally by 2030, with vaccination as a key tool
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