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NAFDAC have banned this DRUG..... Even when consume in the right dose, can cause HEPATOTOXICITY and may require LIVER TRANSPLANT.
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Yes. Ketoconazole can cause liver injury, and in some cases it can be serious.
The risk is particularly important with oral ketoconazole tablets. Liver injury is much less of a concern with ketoconazole creams or shampoos, because very little is absorbed into the bloodstream.

Possible warning signs of liver injury include:
Yellow eyes or skin
Dark urine
Pale stools
Severe or persistent nausea
Loss of appetite
Unusual tiredness
Pain in the upper-right abdomen

If you're taking oral ketoconazole, it should generally only be used under medical supervision, with attention to liver function and drug interactions.

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The important thing is to distinguish between oral ketoconazole and ketoconazole cream or shampoo. The liver concern is much greater with the tablets because they enter the bloodstream.

The distinction between tablets and topical ketoconazole should be emphasized. Someone reading “ketoconazole damages the liver” might become unnecessarily afraid of using a prescribed cream.

Another thing is drug interaction. Someone already taking other medicines should tell their doctor or pharmacist before using oral ketoconazole..